S Antibody

As low as $166.00
In stock
Product Code
CSB-PA336163EA01HIY
Product Code:CSB-PA336163EA01HIY
Size:50μg/100μg
Host Species:Rabbit
Species reactivity:Human coronavirus OC43
Test application:ELISA
More Information
Aliases Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1 (90B); Spike protein S2 (90A)], S
Target/Protein S
Uniprot NO. P36334
Immunogen Recombinant Human coronavirus OC43 Spike glycoprotein protein (15-344AA)
Host species Rabbit
Species Reactivity Human coronavirus OC43
Clonality Polyclonal
Isotype IgG
Applications ELISA
Background S1 attaches the virion to the cell membrane by interacting with sialic acid-containing cell receptors,initiating the infection. S2 is a class I viral fusion protein. Under the current model,the protein has at least 3 conformational states: pre-fusion native state,pre-hairpin intermediate state,and post-fusion hairpin state. During viral and target cell membrane fusion,the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure,positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
Conjugates Non-conjugated
Form Liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

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