Recombinant Human Prokineticin-1 protein(PROK1) (Active)

$98.00
In stock
Product Code
CSB-AP002671HU
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Product Code: CSB-AP002671HU
Size: 5μg/20μg/100μg/250μg
Species: Human
Classification: Cytokine
Express system: E.coli
More Information
Classification Cytokine
Uniprot NO. P58294
PubMed ID 11259612; 11528470; 12975309; 16710414; 15489334; 15340161; 15292351; 17289879; 18339712
Gene Name PROK1,UNQ600/PRO1186
Species Human
AA Sequence AVITGACERD VQCGAGTCCA ISLWLRGLRM CTPLGREGEE CHPGSHKVPF FRKRKHHTCP CLPNLLCSRF PDGRYRCSMD LKNINF
Biologically Active Active
MW of Fusion Proten 9.7 kDa
Expression System E.coli
Purity >98% as determined by SDS-PAGE and HPLC.
Tag info Untagged
Buffer 0.2 μm filtered PBS, pH 7.4, 0.02 % Tween-20,lyophilized
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Relevance Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. {ECO:0000269|PubMed:11259612, ECO:0000269|PubMed:11528470, ECO:0000269|PubMed:15292351, ECO:0000269|PubMed:17289879, ECO:0000269|PubMed:18339712}.

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