Recombinant Mouse Interleukin-21 protein(Il21) (Active)

$112.00
In stock
Product Code
CSB-AP003391MO
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Product Code: CSB-AP003391MO
Size: 2μg/10μg/100μg/250μg
Species: Mouse
Classification: Cytokine
Express system: E.coli
More Information
Classification Cytokine
Uniprot NO. Q9ES17
PubMed ID 11081504; 11970879; 12893770; 15100251
Gene Name Il21
Species Mouse
AA Sequence HKSSPQGPDR LLIRLRHLID IVEQLKIYEN DLDPELLSAP QDVKGHCEHA AFACFQKAKL KPSNPGNNKT FIIDLVAQLR RRLPARRGGK KQKHIAKCPS CDSYEKRTPK EFLERLKWLL QKMIHQHLS
Biologically Active Active
MW of Fusion Proten 15.0 kDa
Expression System E.coli
Purity >98% as determined by SDS-PAGE and HPLC.
Tag info Untagged
Buffer 0.2 m filtered 2 μ PBS, pH 7.4,lyophilized
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Relevance Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. {ECO:0000250, ECO:0000269|PubMed:11970879, ECO:0000269|PubMed:12893770, ECO:0000269|PubMed:15100251}.

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