Recombinant Human Interleukin-1 receptor-like 2(IL1RL2),partial

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CSB-AP004541HU
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Product Code: CSB-AP004541HU
Size: 10μg/50μg/500μg/1mg
Species of origin: Homo sapiens (Human)
Express system: Mammalian cell
More Information
Alternative names Interleukin-1 receptor-like 2;IL1RL2;IL-36 receptor;IL-36R;IL-1Rrp2;IL1R-rp2;
Uniprot NO. Q9HB29
Target/Protein IL1RL2
Species of origin Homo sapiens (Human)
AA Sequence DGCKDIFMKNEILSASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESKRIREGVETHVSFREHNLYTVNITFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFRAY
Activity Data The ED50 as determined by its ability to bind Human IL-1F5 in functional ELISA is less than 50 ug/ml.
Protein description Partial
MW of Fusion Proten 63.1 kDa
Expression Region 20-337aa
Expression System Mammalian Cell
Purity Greater than 95% as determined by SDS-PAGE.
Tag info C-terminal FC-tagged
Storage Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4
Relevance Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene, belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.
Research areas Immunology

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