Recombinant Human Insulin-like growth factor II protein(IGF2) (Active)

$98.00
In stock
Product Code
CSB-AP002551HU
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Product Code: CSB-AP002551HU
Size: 10μg/50μg/100μg/250μg
Species: Human
Classification: Cytokine
Express system: E.coli
More Information
Classification Cytokine
Uniprot NO. P01344
PubMed ID 6382022; 6382021; 2450353; 3002851; 3476948; 3683205; 3881277; 7730145; 16531418; 20842449; 15498874; 14702039; 16554811; 15489334; 3167054; 3653397; 3652904; 658418; 2722836; 7633596; 11448941; 12586351; 15359740; 1569071; 16912056; 19066168; 19838169; 22171320; 23234360; 6189745; 7527339; 18046459
Gene Name IGF2,PP1446
Species Human
AA Sequence AYRPSETLCG GELVDTLQFV CGDRGFYFSR PASRVSRRSR GIVEECCFRS CDLALLETYC ATPAKSE
Biologically Active Active
MW of Fusion Proten 7.5 kDa
Expression System E.coli
Purity >98% as determined by SDS-PAGE and HPLC.
Tag info Untagged
Buffer 0.2 μm filtered 20 mM Tris-HCl, pH 8.0, 150 mM NaCl, with 0.02 % Tween-20,lyophilized
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Relevance The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.; Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.

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