Recombinant Human Insulin-like growth factor I protein(IGF1) (Active)

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Product Code
CSB-AP002561HU
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Product Code: CSB-AP002561HU
Size: 1mg/5mg/20mg
Species: Human
Classification: Cytokine
Express system: E.coli
More Information
Classification Cytokine
Uniprot NO. P05019
PubMed ID 6358902; 3002851; 2935423; 2937782; 3455760; 2082190; 2018498; 1372070; 8495408; 16541075; 15489334; 6382022; 632300; 3242681; 21076856; 24132240; 6189745; 2036417; 1319992; 8857020; 10391209
Gene Name IGF1,IBP1
Species Human
AA Sequence MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA
Biologically Active Active
MW of Fusion Proten 9.1 kDa
Expression System E.coli
Purity >90% as determined by SDS-PAGE and HPLC.
Tag info Untagged
Buffer 0.2 μm filtered 20 mM Tris-HCl, pH 8.0, 150 mM NaCl, with 0.02 % Tween-20,lyophilized
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Relevance The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. {ECO:0000269|PubMed:21076856, ECO:0000269|PubMed:24132240}.

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