Recombinant Human Interleukin-8 protein(CXCL8) (Active)

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Product Code
CSB-AP001761HU
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Product Code: CSB-AP001761HU
Size: 5μg/25μg/100μg/250μg
Species: Human
Classification: Cytokine
Express system: E.coli
More Information
Classification Cytokine
Uniprot NO. P10145
PubMed ID 2953813; 3260265; 2663993; 2664463; 2200751; 14702039; 15489334; 2523801; 2145175; 2648135; 2659722; 1755384; 2655583; 8344717; 3279957; 3480540; 3322281; 2212672; 2007144; 11023497; 11978786; 1639201; 14711052; 18710930; 19608678; 20829347; 2681204; 2184886; 8631339; 10368283; 2182630; 2005614; 1988949; 10707023
Gene Name CXCL8,IL8
Species Human
AA Sequence SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS
Biologically Active Active
MW of Fusion Proten 8.4 kDa
Expression System E.coli
Purity >97% as determined by SDS-PAGE and HPLC.
Tag info Untagged
Buffer 0.2 μm filtered PBS, pH 7.4,lyophilized
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Relevance IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. {ECO:0000269|PubMed:11978786, ECO:0000269|PubMed:2145175, ECO:0000269|PubMed:2212672}.

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