Recombinant Human C-C motif chemokine 21 protein(CCL21) (Active)
$112.00
In stock
Product Code
CSB-AP000941HU
Product Code: CSB-AP000941HU
Size: 5μg/20μg/100μg/250μg
Species: Human
Classification: Cytokine
Express system: E.coli
Size: 5μg/20μg/100μg/250μg
Species: Human
Classification: Cytokine
Express system: E.coli
| Classification | Cytokine |
|---|---|
| Uniprot NO. | O00585 |
| PubMed ID | 9235955; 9257816; 9300671; 9419363; 12975309; 15489334; 9507024; 23341447; 22221265 |
| Gene Name | CCL21,SCYA21,UNQ784/PRO1600 |
| Species | Human |
| AA Sequence | SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P |
| Biologically Active | Active |
| MW of Fusion Proten | 12.2 kDa |
| Expression System | E.coli |
| Purity | >97% as determined by SDS-PAGE and HPLC. |
| Tag info | Untagged |
| Buffer | 0.2 μm filtered PBS, pH 7.4,lyophilized |
| Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
| Relevance | Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
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