UFD1L Antibody

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Product Code
CSB-PA842166ESR1HU
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Product Code:UFD1 Antibody
Size:50μg/100μg
Host Species:Rabbit
Species reactivity:Human
Test application:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
More Information
Aliases Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1), UFD1
Alternatives to SCBT sc-292639/sc-9295/sc-9296
Target/Protein UFD1L
Uniprot NO. Q92890
Immunogen Recombinant Human Ubiquitin recognition factor in ER-associated degradation protein 1 protein (1-307AA)
Immunogen Species Human
Host species Rabbit
Species Reactivity Human
Clonality Polyclonal
Isotype IgG
Modification unmodified
Applications WB, IHC, ELISA
Background Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures.
Conjugates Non-conjugated
Form Liquid
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Cell Biology

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