TRPM2 Antibody

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Product Code: CSB-PA007779LA01HU
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Human|Mouse
Test application: ELISA, WB, IHC, IF;Recommended dilution:WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200
More Information
Aliases Transient receptor potential cation channel subfamily M member 2 (Estrogen-responsive element-associated gene 1 protein) (Long transient receptor potential channel 2) (LTrpC-2) (LTrpC2) (Transient receptor potential channel 7) (TrpC7) (Transient receptor potential melastatin 2), TRPM2, EREG1 KNP3 LTRPC2 TRPC7
Alternatives to SCBT sc-19198
Target/Protein TRPM2
Uniprot NO. O94759
Immunogen Recombinant Human Transient receptor potential cation channel subfamily M member 2 protein (60-119AA)
Immunogen Species Human
Host species Rabbit
Species Reactivity Human, Mouse
Clonality Polyclonal
Isotype IgG
Modification unmodified
Applications WB, IHC, IF, ELISA
Background Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.
Conjugates Non-conjugated
Form Liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Signal Transduction

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