speB Antibody

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Product Code: CSB-PA676488LA01SBAF
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Streptococcus pyogenes serotype M28
Test application: ELISA, WB;Recommended dilution:WB:1:500-1:5000
More Information
Aliases Streptopain (EC (Exotoxin type B) (SPE B) (Streptococcal cysteine proteinase) (Streptococcus peptidase A) (SPP)
Alternatives to SCBT N/A
Target/Protein speB
Uniprot NO. Q48R29
Immunogen Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA)
Immunogen Species Streptococcus pyogenes serotype M28
Host species Rabbit
Species Reactivity Streptococcus pyogenes serotype M28
Clonality Polyclonal
Isotype IgG
Modification unmodified
Applications WB, ELISA
Background Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing (By similarity).
Conjugates Non-conjugated
Form Liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Others

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