PSME3 Antibody

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Product Code
CSB-PA13674A0Rb
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Product Code:PSME3 Antibody
Size:50μg/100μg
Host Species:Rabbit
Species reactivity:Human
Test application:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
More Information
Aliases Proteasome activator complex subunit 3 (11S regulator complex subunit gamma) (REG-gamma) (Activator of multicatalytic protease subunit 3) (Ki nuclear autoantigen) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma)
Alternatives to SCBT sc-133876/sc-21273/sc-21274
Target/Protein PSME3
Uniprot NO. P61289
Immunogen Recombinant Human Proteasome activator complex subunit 3 protein (2-252AA)
Immunogen Species Human
Host species Rabbit
Species Reactivity Human
Clonality Polyclonal
Isotype IgG
Modification unmodified
Applications IHC, IF, ELISA
Background Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation.
Conjugates Non-conjugated
Form Liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Cell Biology

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