pfo Antibody

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Product Code: CSB-PA314820HA01CMB
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Clostridium perfringens
Test application: ELISA, WB;Recommended dilution:WB:1:500-1:5000
More Information
Aliases Perfringolysin O (Theta-toxin) (Thiol-activated cytolysin), pfo
Alternatives to SCBT N/A
Target/Protein pfo
Uniprot NO. P0C2E9
Immunogen Recombinant Clostridium perfringens Perfringolysin O protein (29-500AA)
Immunogen Species Clostridium perfringens
Host species Rabbit
Species Reactivity Clostridium perfringens
Clonality Polyclonal
Isotype IgG
Modification unmodified
Applications WB, ELISA
Background Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein assembles into a pre-pore complex. A conformation change leads to insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host cell membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation.
Conjugates Non-conjugated
Form Liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Others

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