NRP1 Antibody

As low as $166.00
In stock
Product Code
CSB-PA016091ESR1HU
Product Code:NRP1 Antibody
Size:50μg/100μg
Host Species:Rabbit
Species reactivity:Human
Test application:ELISA, IHC; Recommended dilution: IHC:1:20-1:200
More Information
Aliases Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304), NRP1
Alternatives to SCBT sc-5541/sc-7239
Target/Protein NRP1
Uniprot NO. O14786
Immunogen Recombinant Human Neuropilin-1 protein (684-923AA)
Immunogen Species Human
Host species Rabbit
Species Reactivity Human
Clonality Polyclonal
Isotype IgG
Modification unmodified
Applications IHC, ELISA
Background The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.
Conjugates Non-conjugated
Form Liquid
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Cardiovascular

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