N Antibody
As low as
$166.00
In stock
Product Code
CSB-PA318492LA01JAM
Product Code: CSB-PA318492LA01JAM
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Junin mammarenavirus
Test application: ELISA, WB;Recommended dilution:WB:1:500-1:5000
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Junin mammarenavirus
Test application: ELISA, WB;Recommended dilution:WB:1:500-1:5000
Aliases | Nucleoprotein (Nucleocapsid protein) (Protein N) |
---|---|
Alternatives to SCBT | N/A |
Target/Protein | N |
Uniprot NO. | P14239 |
Immunogen | Recombinant Junin mammarenavirus Nucleoprotein protein (1-564AA) |
Immunogen Species | Junin mammarenavirus |
Host species | Rabbit |
Species Reactivity | Junin mammarenavirus |
Clonality | Polyclonal |
Isotype | IgG |
Modification | unmodified |
Applications | WB, ELISA |
Background | Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation (By similarity). Interacts with host IKBKE (via Protein kinase domain); the interaction inhibits IKBKE kinase activity. |
Conjugates | Non-conjugated |
Form | Liquid |
Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Research areas | Others |
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N Antibody Images

Western Blot
Positive WB detected in Recombinant protein
All lanes:N antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
predicted band size: 64 KDa
observed band size: 64 KDa
Positive WB detected in Recombinant protein
All lanes:N antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
predicted band size: 64 KDa
observed band size: 64 KDa