MAPT Antibody

$166.00
In stock
Product Code
CSB-PA11169A0Rb
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Product Code: CSB-PA11169A0Rb
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Human|Mouse
Test application: ELISA, WB, IHC, IF;Recommended dilution:WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200
More Information
Aliases Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU
Alternatives to SCBT sc-1995/sc-1996/sc-5587
Target/Protein MAPT
Uniprot NO. P10636
Immunogen Recombinant human Microtubule-associated protein tau protein (33-166AA)
Immunogen Species Human
Host species Rabbit
Species Reactivity Human, Mouse
Clonality Polyclonal
Isotype IgG
Modification unmodified
Applications WB, IHC, IF, ELISA
Background Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Conjugates Non-conjugated
Form Liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Neuroscience

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