KARS Antibody

$166.00
In stock
Product Code
CSB-PA04689A0Rb
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Product Code: CSB-PA04689A0Rb
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Human
Test application: ELISA, WB, IHC, IF;Recommended dilution:WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200
More Information
Aliases Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS, KARS, KIAA0070
Alternatives to SCBT sc-79253/sc-79256/sc-98559
Target/Protein KARS
Uniprot NO. Q15046
Immunogen Recombinant human Lysine--tRNA ligase protein (101-400AA)
Immunogen Species Human
Host species Rabbit
Species Reactivity Human
Clonality Polyclonal
Isotype IgG
Modification unmodified
Applications WB, IHC, IF, ELISA
Background Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of diadenosine oligophosphate (Ap4A), a signaling molecule involved in the activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA(3)(Lys), the primer for reverse transcription initiation.
Conjugates Non-conjugated
Form Liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Epigenetics and Nuclear Signaling

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