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Aliases | Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84), HSP90AB1, HSP90B HSPC2 HSPCB |
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Alternatives to SCBT | sc-1057 |
Target/Protein | HSP90AB1 |
Uniprot NO. | P08238 |
Immunogen | Recombinant Human human Heat shock protein HSP 90-beta protein (150-355AA) |
Immunogen Species | Human |
Host species | Rabbit |
Species Reactivity | Human, Mouse, Rat, Zebrafish |
Clonality | Polyclonal |
Isotype | IgG |
Modification | unmodified |
Applications | WB, IHC, IF, ELISA |
Background | Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. |
Conjugates | Non-conjugated |
Form | Liquid |
Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Research areas | Signal Transduction |