FAS Antibody

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Product Code
CSB-PA06354A0Rb
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Product Code:FAS Antibody
Size:50μg/100μg
Host Species:Rabbit
Species reactivity:Human
Test application:ELISA, IHC, IF; Recommended dilution: IHC:1:50-1:200, IF:1:50-1:500
More Information
Aliases Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95), FAS
Alternatives to SCBT sc-714/sc-715/sc-7886
Target/Protein FAS
Uniprot NO. P25445
Immunogen Recombinant Human Tumor necrosis factor receptor superfamily member 6 protein (26-171AA)
Immunogen Species Human
Host species Rabbit
Species Reactivity Human
Clonality Polyclonal
Isotype IgG
Modification unmodified
Applications IHC, IF, ELISA
Background Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Conjugates Non-conjugated
Form Liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Cell Biology

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