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ERAP1 Antibody
As low as
$166.00
In stock
Product Code
CSB-PA007760LA01HU
Product Code: CSB-PA007760LA01HU
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Human
Test application: ELISA, IHC, IF;Recommended dilution:IHC:1:20-1:200, IF:1:50-1:200
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Human
Test application: ELISA, IHC, IF;Recommended dilution:IHC:1:20-1:200, IF:1:50-1:200
| Aliases | Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator), ERAP1 |
|---|---|
| Alternatives to SCBT | sc-26884/sc-26885/sc-98254 |
| Target/Protein | ERAP1 |
| Uniprot NO. | Q9NZ08 |
| Immunogen | Recombinant Human Endoplasmic reticulum aminopeptidase 1 protein (642-941AA) |
| Immunogen Species | Human |
| Host species | Rabbit |
| Species Reactivity | Human |
| Clonality | Polyclonal |
| Isotype | IgG |
| Modification | unmodified |
| Applications | WB, IHC, IF, ELISA |
| Background | Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney. |
| Conjugates | Non-conjugated |
| Form | Liquid |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Research areas | Immunology |
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ERAP1 Antibody Images
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA007760LA01HU at dilution of 1:100
Western Blot
Positive WB detected in: K562 whole cell lysate
All lanes: ERAP1 antibody at 3.2μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 108 kDa
Observed band size: 108 kDa
Positive WB detected in: K562 whole cell lysate
All lanes: ERAP1 antibody at 3.2μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 108 kDa
Observed band size: 108 kDa
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA007760LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA007760LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)