Product Code: CSB-PA00174A0Rb
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Human|Mouse|Zebrafish
Test application: ELISA, WB, IHC;Recommended dilution:WB:1:1000-1:5000, IHC:1:20-1:200
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Human|Mouse|Zebrafish
Test application: ELISA, WB, IHC;Recommended dilution:WB:1:1000-1:5000, IHC:1:20-1:200
| Aliases | CTNNB1, CTNNB, OK/SW-cl.35, PRO2286, Beta-catenin |
|---|---|
| Alternatives to SCBT | sc-31000/sc-31001/sc-7199 |
| Target/Protein | CTNNB1 |
| Uniprot NO. | P35222 |
| Immunogen | Recombinant human Catenin beta-1 protein (2-781AA) |
| Immunogen Species | Human |
| Host species | Rabbit |
| Species Reactivity | Human, Mouse, Zebrafish |
| Clonality | Polyclonal |
| Isotype | IgG |
| Modification | unmodified |
| Applications | WB, IHC, ELISA |
| Background | Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton. Involved in signal transduction through the Wnt pathway. Nuclear beta-catenin it involved in transcriptional regulation by association with transcription factors of the TCF/LEF family. |
| Conjugates | Non-conjugated |
| Form | Liquid |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Research areas | Cell Adhesion |
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CTNNB1 Antibody Images
Immunofluorescence staining of HepG2 cells with CSB-PA00174A0Rb at 1:166,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA00174A0Rb at dilution 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA00174A0Rb at dilution 1:100