Cobra venom factor Antibody

$166.00
In stock
Product Code
CSB-PA856221LA01NAF
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Product Code: CSB-PA856221LA01NAF
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Naja kaouthia
Test application: ELISA, WB;Recommended dilution:WB:1:500-1:5000
More Information
Aliases Cobra venom factor (CVF) (CVFk) (Complement C3 homolog) [Cleaved into: Cobra venom factor alpha chain; Cobra venom factor gamma chain; Cobra venom factor beta chain]immunogen_species=Naja kaouthia
Alternatives to SCBT N/A
Target/Protein Cobra venom factor
Uniprot NO. Q91132
Immunogen Recombinant Naja kaouthia Cobra venom factor protein (733-984AA)
Immunogen Species Naja kaouthia
Host species Rabbit
Species Reactivity Naja kaouthia
Clonality Polyclonal
Isotype IgG
Modification unmodified
Applications WB, ELISA
Background Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity.
Conjugates Non-conjugated
Form Liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Others

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