Product Code: CSB-PA001827LA01HU
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Human|Mouse
Test application: ELISA, WB, IHC, IF;Recommended dilution:WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Size: 50μg/100μg
Host Species: Rabbit
Species reactivity: Human|Mouse
Test application: ELISA, WB, IHC, IF;Recommended dilution:WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200
| Aliases | Aminopeptidase N, AP-N, hAPN, Alanyl aminopeptidase, Aminopeptidase M, AP-M, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, gp150, CD13, ANPEP, APN, CD13, PEPN |
|---|---|
| Alternatives to SCBT | sc-15360/sc-6995 |
| Target/Protein | ANPEP |
| Uniprot NO. | P15144 |
| Immunogen | Recombinant Human Aminopeptidase N protein (34-219AA) |
| Immunogen Species | Human |
| Host species | Rabbit |
| Species Reactivity | Human, Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Modification | unmodified |
| Applications | WB, IHC, IF, ELISA |
| Background | Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types, responsible for the processing of peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection. |
| Conjugates | Non-conjugated |
| Form | Liquid |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Research areas | Immunology |
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ANPEP Antibody Images
Western Blot
Positive WB detected in:Mouse kidney tissue
All lanes:ANPEP antibody at 3.4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 110 KDa
Observed band size: 110 KDa
Positive WB detected in:Mouse kidney tissue
All lanes:ANPEP antibody at 3.4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 110 KDa
Observed band size: 110 KDa
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA001827LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA001827LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA001827LA01HU at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)