* Online payment is not available now. Please send your PO to order@cusabio.com. We will deal with it soon. * The information on this page is not updated. For the latest product information, please search on cusabio.com with the product code.
NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3, NFKBIA, IKBA, MAD3, NFKBI
Target/Protein
Phospho-NFKBIA
Uniprot NO.
P25963
Immunogen
A synthesized peptide derived from human Phospho-NFKBIA (S32)
Clonality
Monoclonal
Applications
WB, IF, ELISA
Background
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Conjugates
Non-conjugated
Form
Liquid
Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage
Upon receipt, store at -20 °C or -80 °C. Avoid repeated freeze.
