PD-L1 Monoclonal Antibody

As low as $210.00
In stock
Product Code
Product Code:CSB-MA878942A1m
Host Species:Mouse
Species reactivity:Human
Test application:ELISA, WB, IHC, IF, FC; Recommended dilution: WB:1:1000-1:5000, IHC:1:50-1:200, IF:1:50-1:200, FC:1:100-1:500
More Information
Aliases Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (B7 homolog 1) (B7-H1) (CD antigen CD274), CD274, B7H1 PDCD1L1 PDCD1LG1 PDL1
Target/Protein PD-L1
Uniprot NO. Q9NZQ7
Immunogen Recombinant Human Programmed cell death 1 ligand 1 protein (19-238AA)
Host species Mouse
Clonality Monoclonal
Applications WB, IHC, IF, ELISA, FC
Background Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (PubMed:28813417, PubMed:28813410). Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077)
Conjugates Non-conjugated
Form Liquid
Buffer Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage Upon receipt, store at -20 °C or -80 °C. Avoid repeated freeze.

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