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N Antibody

As low as $166.00
In stock
Product Code
CSB-PA321352LA01RAI
Product Code:CSB-PA321352LA01RAI
Size:50μg/100μg
Host Species:Rabbit
Species reactivity:Rabies virus
Test application:ELISA
More Information
Aliases Nucleoprotein (NP) (Nucleocapsid protein) (Protein N), N
Target/Protein N
Uniprot NO. P15197
Immunogen Recombinant Rabies virus Nucleoprotein protein (1-450AA)
Host species Rabbit
Species Reactivity Rabies virus
Clonality Polyclonal
Isotype IgG
Applications ELISA
Background Encapsidates the genome in a ratio of one protein N per nine ribonucleotides,protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction with protein P abolishes any non-specific RNA binding,and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA,with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction,and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication,encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases
Conjugates Non-conjugated
Form Liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

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