RBP4 Monoclonal Antibody

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Product Code:CSB-MA070501A0m
Host Species:Mouse
Species reactivity:Human|Mouse
Test application:ELISA, WB, IHC;Recommended dilution:WB:1:500-1:5000, IHC:1:50-1:500
More Information
Aliases Plasma retinol-binding protein, PRBP, RBP, RBP4, PRO2222
Alternatives to SCBT sc-48384/sc-69795/sc-46688
Target/Protein RBP4
Uniprot NO. P02753
Immunogen Recombinant Human Retinol-binding protein 4 protein
Immunogen Species Human
Host species Mouse
Species Reactivity Human, Mouse
Clonality Monoclonal
Isotype IgG1
Modification unmodified
Applications WB, IHC, ELISA
Background Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.
Conjugates Non-conjugated
Form liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Cardiovascular

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