CD14 Monoclonal Antibody

$210.00
In stock
Product Code
CSB-MA0048791A0m
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Product Code:CSB-MA0048791A0m
Size:50μg/100μg
Host Species:Mouse
Species reactivity:Human
Test application:ELISA, IHC;Recommended dilution:IHC:1:50-1:500
More Information
Aliases CD14, CD14 molecule
Alternatives to SCBT sc-58951/sc-19588/sc-7328/sc-52457/sc-1182
Target/Protein CD14
Uniprot NO. P08571
Immunogen Recombinant CD14 Protein
Immunogen Species Human
Host species Mouse
Species Reactivity Human
Clonality Monoclonal
Isotype IgG2b
Modification unmodified
Applications IHC, ELISA
Background As a component of the innate immune system, the cell surface glycoprotein CD14 is a myelomonocytic differentiation antigen preferentially expressed on monocytes, macrophages, and activated granulocytes. CD14 exists as two forms, either anchored into the membrane by a GPI-anchor tail (mCD14) or present as a soluble form (sCD14) in normal serum and body fluids. CD14 was first described as a pattern recognition receptor for lipopolysaccharide (LPS) and a variety of ligands derived from different microbial sources, along with the co-receptors Toll-like receptor TLR 4 and MD-2. The binding of CD14 and LPS depends on the presence and catalytic activity of lipopolysaccharide-binding protein (LBP). Besides its endotoxin signaling function, CD14 has been proposed to be involved in various biological processes, including transportation of other lipids, cell-cell interaction during different immune responses, as well as recognition of apoptotic cells. Multiple transcript variants resulting from alternative splicing encode the same isoform of CD14.
Conjugates Non-conjugated
Form liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Immunology

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