CCL2 Monoclonal Antibody

$210.00
In stock
Product Code
CSB-MA058641A0m
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Product Code:CSB-MA058641A0m
Size:50μg/100μg
Host Species:Mouse
Species reactivity:Human
Test application:ELISA, IHC;Recommended dilution:IHC:1:50-1:500
More Information
Aliases Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, Small-inducible cytokine A2, CCL2, MCP1, SCYA2
Alternatives to SCBT sc-52877/sc-377082/sc-130328/sc-32781/sc-32771/sc-32819/sc-32786
Target/Protein CCL2
Uniprot NO. P13500
Immunogen Recombinant Human C-C motif chemokine 2
Immunogen Species Human
Host species Mouse
Species Reactivity Human
Clonality Monoclonal
Isotype IgG2b
Modification unmodified
Applications IHC, ELISA
Background Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. [1] "Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF)."Furutani Y., Nomura H., Notake M., Oyamada Y., Fukui T., Yamada M., Larsen C.G., Oppenheim J.J., Matsushima K.Biochem. Biophys. Res. Commun. 159:249-255(1989) [2] "The human homolog of the JE gene encodes a monocyte secretory protein."Rollins B.J., Stier P., Ernst T., Wong G.G.Mol. Cell. Biol. 9:4687-4695(1989) [3] "Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE."Yoshimura T., Yuhki N., Moore S.K., Appella E., Lerman M.I., Leonard E.J.FEBS Lett. 244:487-493(1989)
Conjugates Non-conjugated
Form liquid
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas Immunology

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