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CD44 Antibody

As low as $210.00
In stock
Product Code
CSB-RA004938A0HU
Product Code:CSB-RA004938A0HU
Size:50μl/100μl
Host Species:
Species reactivity:Human
Test application:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500
More Information
Aliases CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, CD44, LHR, MDU2, MDU3, MIC4
Target/Protein CD44
Uniprot NO. P16070
Immunogen A synthesized peptide
Clonality Monoclonal
Applications WB, IHC, ELISA
Background Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).
Conjugates Non-conjugated
Form Liquid
Buffer Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Upon receipt, store at -20 °C or -80 °C. Avoid repeated freeze.

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