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CD22 Antibody

As low as $210.00
In stock
Product Code
CSB-RA962691A0HU
Product Code:CSB-RA962691A0HU
Size:50μl/100μl
Host Species:
Species reactivity:Human
Test application:ELISA, IHC; Recommended dilution: IHC:1:50-1:200
More Information
Aliases B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22), CD22, SIGLEC2
Target/Protein CD22
Uniprot NO. P20273
Immunogen A synthesized peptide derived from human CD22
Clonality Monoclonal
Applications IHC, ELISA
Background Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Conjugates Non-conjugated
Form Liquid
Buffer Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Upon receipt, store at -20 °C or -80 °C. Avoid repeated freeze.

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