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BCL2L1 (Ab-62) Antibody

As low as $297.00
In stock
Product Code
Product Code:CSB-PA923588
Size: 100ul
Host Species:Rabbit
Species reactivity:Human, Mouse, Rat
Test application:ELISA, WB;WB:1:500-1:1000
More Information
Aliases Apoptosis regulator Bcl-X
Target/Protein BCL2L1
Uniprot NO. Q07817
Immunogen Peptide sequence around aa.60~64 (A-D-S-P-A) derived from human BCL-XL .
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Applications WB, ELISA
Background Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis.<br/><br/>Basu A, et.al.( 2003) Mar 13; 538(1-3): 41-7<br/>Cheng E.H.-Y. et.al. (1996) Nature 379:554-556.<br/>Sattler M. et.al. (1997), Science 275:983-986.<br/>Muchmore S.W.et.al (1996).Nature 381:335-341<br/>Yu J., Zhang L. Mol. (2001)Cell 7:673-682<br/>
Conjugates Non-conjugated
Form liquid
Buffer Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Upon receipt, store at -20 °C or -80 °C. Avoid repeated freeze.

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