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BCL2L1 (Ab-62) Antibody
As low as
$297.00
In stock
Product Code
CSB-PA923588
Product Code:CSB-PA923588
Size: 100ul
Host Species:Rabbit
Species reactivity:Human, Mouse, Rat
Test application:ELISA, WB;WB:1:500-1:1000
Size: 100ul
Host Species:Rabbit
Species reactivity:Human, Mouse, Rat
Test application:ELISA, WB;WB:1:500-1:1000
| Aliases | Apoptosis regulator Bcl-X |
|---|---|
| Target/Protein | BCL2L1 |
| Uniprot NO. | Q07817 |
| Immunogen | Peptide sequence around aa.60~64 (A-D-S-P-A) derived from human BCL-XL . |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | WB, ELISA |
| Background | Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis.<br/><br/>Basu A, et.al.( 2003) Mar 13; 538(1-3): 41-7<br/>Cheng E.H.-Y. et.al. (1996) Nature 379:554-556.<br/>Sattler M. et.al. (1997), Science 275:983-986.<br/>Muchmore S.W.et.al (1996).Nature 381:335-341<br/>Yu J., Zhang L. Mol. (2001)Cell 7:673-682<br/> |
| Conjugates | Non-conjugated |
| Form | liquid |
| Buffer | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage | Upon receipt, store at -20 °C or -80 °C. Avoid repeated freeze. |
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