BCL2 (Ab-56) Antibody

As low as $297.00
In stock
Product Code
CSB-PA187601
Product Code:CSB-PA187601
Size: 100ul
Host Species:Rabbit
Species reactivity:Human
Test application:ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200
More Information
Aliases BCL2
Target/Protein BCL2
Uniprot NO. P10415
Immunogen Peptide sequence around aa. 54~58 (G-H-T-P-H) derived from Human BCL-2.
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Applications WB, IHC, IF, ELISA
Background Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).<br/><br/>Ling, Y. H. et al. (1998) J. Biol. Chem. 273, 18984-18991.<br/>Huang, S.J. and Cidlowski, J.A. (2002) FASEB 16, 825-832.<br/>Deng, X. et al. (2001) J. Biol. Chem. 276, 23681-23688.<br/>Huang ST,et al. (2002) FASEB J Jun; 16(8): 825-32.<br/>Yamamoto, K. et al. (1999) Mol. Cell. Biol. 19, 8469-8478.<br/>
Conjugates Non-conjugated
Form liquid
Buffer Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Upon receipt, store at -20 °C or -80 °C. Avoid repeated freeze.

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