BACE2 Polyclonal Antibody- CUSABIO

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Aliases	Beta-secretase 2 (EC 3.4.23.45) (Aspartic-like protease 56 kDa) (Aspartyl protease 1) (ASP1) (Asp 1) (Beta-site amyloid precursor protein cleaving enzyme 2) (Beta-site APP cleaving enzyme 2) (Down region aspartic protease) (DRAP) (Memapsin-1) (Membrane-associated aspartic protease 1) (Theta-secretase), BACE2, AEPLC ALP56 ASP21
Alternatives to SCBT	sc-10048/sc-10049/sc-10051/sc-15388
Target/Protein	BACE2
Uniprot NO.	Q9Y5Z0
Immunogen	Recombinant Human Beta-secretase 2 protein (84-157AA)
Immunogen Species	Human
Host species	Rabbit
Species Reactivity	Human, Rat
Clonality	Polyclonal
Isotype	IgG
Modification	unmodified
Applications	WB, IHC, IF, ELISA
Background	Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP,between residues 690 and 691,leading to the generation and extracellular release of beta-cleaved soluble APP,and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
Conjugates	Non-conjugated
Form	Liquid
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Research areas	Neuroscience

BACE2 Antibody