ANAPC1 Antibody

As low as $297.00
In stock
Product Code
CSB-PA105829
Product Code:CSB-PA105829
Size: 100ul
Host Species:Rabbit
Species reactivity:Human, Mouse
Test application:ELISA, IHC;IHC:1:50-1:100
More Information
Aliases ANAPC1; Anaphase promoting complex subunit 1; ANC1; Cyclosome subunit 1; Mitotic checkpoint regulator
Target/Protein ANAPC1
Uniprot NO. Q9H1A4
Immunogen Synthesized peptide derived from Internal of human APC1.
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Applications IHC, ELISA
Background Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<br/><br/>Joergensen P.M., Gene 262:51-59(2001).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Kraft C., EMBO J. 22:6598-6609(2003).<br/>
Conjugates Non-conjugated
Form liquid
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Upon receipt, store at -20 °C or -80 °C. Avoid repeated freeze.

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