ADCY6 Antibody

As low as $166.00
In stock
Product Code
CSB-PA001342LA01HU
Product Code:CSB-PA001342LA01HU
Size:50μg/100μg
Host Species:Rabbit
Species reactivity:Human
Test application:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
More Information
Aliases Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase), ADCY6, KIAA0422
Target/Protein ADCY6
Uniprot NO. O43306
Immunogen Recombinant Human Adenylate cyclase type 6 protein (9-118AA)
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Applications IHC, IF, ELISA
Background Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:17916776, PubMed:17110384). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells (PubMed:17916776). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion (By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA. This promotes increased phosphorylation of various proteins, including AKT. Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility. May contribute to normal heart function (By similarity). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol (PubMed:17916776). Contributes to bone cell responses to mechanical stimuli (By similarity).
Conjugates Non-conjugated
Form Liquid
Buffer Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage Upon receipt, store at -20 °C or -80 °C. Avoid repeated freeze.

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